Quercetin
Bone Cancer
1.Quercetin Inhibits Cell Migration and Invasion in Human Osteosarcoma Cells
2.Autophagy Inhibition Promotes Quercetin Induced Apoptosis in MG-63 Human Osteosarcoma cells
3.Evaluation of Quercetin as a Potential Drug in Osteosarcoma Treatment
Breast Cancer
1.Quercetin Suppresses Twist to Induce Apoptosis in MCF-7 Breast Cancer Cells
2.Quercetin reverses tamoxifen resistance in breast cancer cells
Cervical Cancer
In Vitro
1. Prediction of the Mechanisms by Which Quercetin Enhances Cisplatin Action in Cervical Cancer: A Network Pharmacology Study and Experimental Validation (2022)
2. Quercetin-3-Glucoside Extracted from Apple Pomace Induces Cell Cycle Arrest and Apoptosis by Increasing Intracellular ROS Levels (2021)
3. EGFR and ERK activation resists flavonoid quercetin induced anticancer activities in human cervical cancer cells in vitro (2021)
4. Quercetin-Loaded Luminescent Hydroxyapatite Nanoparticles for Theranostic Application in Monolayer and Spheroid Cultures of Cervical Cancer Cell Line In Vitro (2021)
5. Screening of Therapeutic Candidate Genes of Quercetin for Cervical Cancer and Analysis of Their Regulatory Network (2021)
6. Effects of Quercetin on the Efficacy of Various Chemotherapeutic Drugs in Cervical Cancer Cells (2021)
7. The effect of quercetin on cervical cancer cells as determined by inducing tumor endoplasmic reticulum stress and apoptosis and its mechanism of action (2021)
8. Quercetin induces G2 phase arrest and apoptosis with the activation of p53 in an E6 expression independent manner in HPV positive human cervical cancer derived cells (2019)
9. Quercetin modifies 5′CpG promoter methylation and reactivates various tumor suppressor genes by modulating epigenetic marks in human cervical cancer cells (2019)
10. Quercetin modulates signaling pathways and induces apoptosis in cervical cancer cells (2019)
11. Quercetin induces cell death in cervical cancer by reducing O-GlcNAcylation of adenosine monophosphate-activated protein kinase (2018)
12. Quercetin and aconitine synergistically induces the human cervical carcinoma HeLa cell apoptosis via endoplasmic reticulum (ER) stress pathway (2018)
13. Dietary flavonoids, luteolin and quercetin, inhibit invasion of cervical cancer by reduction of UBE2S through epithelial–mesenchymal transition signaling (2017)
14. The critical role of quercetin in autophagy and apoptosis in HeLa cells (2015)
15. Effect of Quercetin on RAC1 Gene Expression as a Marker of Metastasis in Cervical Cancer Cells (2015)
16. Combined treatment with quercetin and imperatorin as a potent strategy for killing HeLa and Hep-2 cells (2014)
17. Antioxidant action and cytotoxicity on HeLa and NIH-3T3 cells of new quercetin derivatives (2013)
18. Quercetin induces cytochrome-c release and ROS accumulation to promote apoptosis and arrest the cell cycle in G2/M, in cervical carcinoma: signal cascade and drug-DNA interaction (2013)
19. Anticancer Activity of a Quercetin-based Polymer Towards HeLa Cancer Cells (2012)
20. The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-κB inhibition (2010)
In Vivo
1. The effect of quercetin nanoparticle on cervical cancer progression by inducing apoptosis, autophagy and anti-proliferation via JAK2 suppression (2016)
2. Effect of Quercetin on Breeding and Apoptosis of Cervical Cancer HeLa Cell and on Growth of Transplanted Tumor in Nude Mice (2007)
3. Chemopreventive Activity of Quercetin During Carcinogenesis in Cervix Uteri in Mice (2000)
Cholangiocarcinoma
1. Quercetin Enhances Phenformin in Inhibition of Cholangiocarcinoma Cell Growth (2020)
2. New approach for treatment of primary liver tumors: The role of quercetin (2016)
3. Quercetin and EGCG Exhibit Chemopreventive Effects in Cholangiocarcinoma Cells via Suppression of JAK/STAT Signaling Pathway (2013)
Colorectal Cancer
In Vitro
1. Quercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis (2015)
2. Quercetin induces cell cycle arrest and apoptosis in CD133+ cancer stem cells of human colorectal HT29 cancer cell line and enhances anticancer effects of doxorubicin (2014)
3. Quercetin induces human colon cancer cells apoptosis by inhibiting the nuclear factor‑kappa B Pathway (2014)
4. Resveratrol and Quercetin in Combination Have Anticancer Activity in Colon Cancer Cells and Repress Oncogenic microRNA-27a (2012)
5. The Pro-Apoptotic Effect of Quercetin in Cancer Cell Lines Requires ERb-Dependent Signals (2011)
6. Quercetin Inhibits Human DLD-1 Colon Cancer Cell Growth and Polyamine Biosynthesis (2010)
7. Apoptotic Effect of Quercetin on HT-29 Colon Cancer Cells via the AMPK Signaling Pathway (2010)
8. Quercetin Inhibit Human SW480 Colon Cancer Growth in Association with Inhibition of Cyclin D1 and Survivin Expression through Wnt/β-Catenin Signaling Pathway (2009)
9. Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts (2007)
10. A preliminary investigation demonstrating the effect of quercetin on the expression of genes related to cell-cycle arrest, apoptosis and xenobiotic metabolism in human CO115 colon-adenocarcinoma cells using DNA microarray (2006)
11. Quercetin mediates preferential degradation of oncogenic Ras and causes autophagy in Ha-RAS-transformed human colon cells (2006)
12. NAG-1 up-regulation mediated by EGR-1 and p53 is critical for quercetin-induced apoptosis in HCT116 colon carcinoma cells (2006)
13. The effects of quercetin on SW480 human colon carcinoma cells: a proteomic study (2005)
14. Protein expression profiling identifies molecular targets of quercetin as a major dietary flavonoid in human colon cancer cells (2003)
15. Integrated assessment by multiple gene expression analysis of quercetin bioactivity on anticancer-related mechanisms in colon cancer cells in vitro (2002)
16. QUERCETIN INHIBITS p21-RAS EXPRESSION IN HUMAN COLON CANCER CELL LINES AND IN PRIMARY COLORECTAL TUMORS (1999)
In Vivo
1. Quercetin Suppresses AOM/DSS-Induced Colon Carcinogenesis through Its Anti-Inflammation Effects in Mice (2020)
2. Anticancer and apoptosis‑inducing effects of quercetin in vitro and in vivo (2017)
3. Quercetin Confers Tumoricidal Activity Through Multipathway Mechanisms in A N-Methylnitrosourea Rat Model of Colon Cancer (2016)
4. Possible Protective Effects of Quercetin and Sodium Gluconate Against Colon Cancer Induction by Dimethylhydrazine in Mice (2015)
5. Quercetin, a Natural Flavonoid Interacts with DNA, Arrests Cell Cycle and Causes Tumor Regression by Activating Mitochondrial Pathway of Apoptosis (2015)
6. Quercetin enhances hypoxia-mediated apoptosis via direct inhibition of AMPK activity in HCT116 colon cancer (2012)
7. Apoptotic Effect of Quercetin on HT-29 Colon Cancer Cells via the AMPK Signaling Pathway (2010)
8. Quercetin May Suppress Rat Aberrant Crypt Foci Formation by Suppressing Inflammatory Mediators That Influence Proliferation and Apoptosis (2008)
9. Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon (1999)
Clinical Trials
1. Dietary Flavonoids and the Risk of Colorectal Cancer: An Updated Meta-Analysis of Epidemiological Studies (2018)
2. Quercetin: A functional dietary flavonoid with potential chemo-preventive properties in colorectal cancer (2017)
Oral Cancer
1.Efficacy of quercetin against chemically induced murine oral squamous cell carcinoma
2.Quercetin Inhibits Migration and Invasion of SAS Human Oral Cancer Cells through Inhibition of NF-κB and Matrix Metalloproteinase-2/-9 Signaling Pathways
Ovarian Cancer
In Vitro
1. Telomerase inhibitor MST-312 and quercetin synergistically inhibit cancer cell proliferation by promoting DNA damage (2023)
2. Quercetin attenuates metastatic ability of human metastatic ovarian cancer cells via modulating multiple signaling molecules involved in cell survival, proliferation, migration and adhesion (2021)
3. Functionalized Graphene Oxide as a Nanocarrier for Dual Drug Delivery Applications: The Synergistic Effect of Quercetin and Gefitinib Against Ovarian Cancer Cells (2019)
4. Formulation and evaluation of mixed polymeric micelles of quercetin for treatment of breast, ovarian, and multidrug resistant cancers (2018)
5. Effect of Quercetin on Cell Cycle and Cyclin Expression in Ovarian Carcinoma and steosarcoma Cell Lines (2015)
6. Monofunctional Platinum-containing Pyridine-based Ligand Acts Synergistically in Combination with the Phytochemicals Curcumin and Quercetin in Human Ovarian Tumour Models (2015)
7. Effect of quercetin on the proliferation of the human ovarian cancer cell line SKOV-3 in vitro (2015)
8. Quercetin induces the apoptosis of human ovarian carcinoma cells by upregulating the expression of microRNA 145 (2015)
9. Synergism from Combinations of tris(benzimidazole) monochloroplatinum(II) Chloride with Capsaicin, Quercetin, Curcumin and Cisplatin in Human Ovarian Cancer Cell Lines (2014)
10. Synergism from Combinations of Cisplatin and Oxaliplatin with Quercetin and Thymoquinone in Human Ovarian Tumour Models (2011)
In Vivo
1. Quercetin suppresses DNA double-strand break repair and enhances the radiosensitivity of human ovarian cancer cells via p53-dependent endoplasmic reticulum stress pathway (2018)
2. Enhancing the anti-ovarian cancer activity of quercetin using a self-assembling micelle and thermosensitive hydrogel drug delivery system (2018)
3. Quercetin induces protective autophagy and apoptosis through ER stress via the p-STAT3/Bcl-2 axis in ovarian cancer (2017)
4. Quercetin enhances apoptotic effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in ovarian cancer cells through reactive oxygen species (ROS) mediated CCAAT enhancer binding protein homologous protein (CHOP)-death receptor 5 pathway (2014)
5. Induction of Apoptosis and Inhibition of Angiogenesis by PEGylated Liposomal Quercetin in Both Cisplatin-Sensitive and Cisplatin-Resistant Ovarian Cancers (2013)
6. Anticancer effect and mechanism of polymer micelle-encapsulated quercetin on ovarian cancer (2012)
Review
1. Quercetin and cancer: new insights into its therapeutic effects on ovarian cancer cells (2020)
2. Overview of biological effects of Quercetin on ovary (2020)
3. Quercetin: a natural compound for ovarian cancer treatment (2019)
4. Quercetin and ovarian cancer: An evaluation based on a systematic review (2016)
Stomach Cancer
In Vitro
1. Systematic Elucidation of the Mechanism of Quercetin against Gastric Cancer via Network Pharmacology Approach (2020)
2. Targeting cell cycle protein in gastric cancer with CDC20siRNA and anticancer drugs (doxorubicin and quercetin) co-loaded cationic PEGylated nanoniosomes (2019)
3. Quercetin Suppresses CYR61-Mediated Multidrug Resistance in Human Gastric Adenocarcinoma AGS Cells (2018)
4. Quercetin induced cell apoptosis and altered gene expression in AGS human gastric cancer cells (2018)
5. Bioinformatics analysis to identify action targets in NCI-N87 gastric cancer cells exposed to quercetin (2018)
6. Quercetin Has Antimetastatic Effects on Gastric Cancer Cells via the Interruption of uPA/uPAR Function by Modulating NF-κb, PKC-δ, ERK1/2, and AMPKα (2018)
7. Quercetin inhibits the growth of human gastric cancer stem cells by inducing mitochondrial-dependent apoptosis through the inhibition of PI3K/Akt signaling (2016)
8. Quercetin-induced apoptosis prevents EBV infection (2015)
9. MicroRNA-143 enhances chemosensitivity of Quercetin through autophagy inhibition via target GABARAPL1 in gastric cancer cells (2015)
10. Combinational Treatment of Curcumin and Quercetin against Gastric Cancer MGC-803 Cells in Vitro (2015)
11. Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells (2014)
12. In vitro effect of quercetin on human gastric carcinoma: Targeting cancer cells death and MDR (2012)
13. Effects of quercetin on the apoptosis of the human gastric carcinoma cells (2012)
14. The effect of quercetin on cell cycle progression and growth of human gastric cancer cells (1990)
In Vivo
1. Quercetin Synergistically Inhibit EBV Associated Gastric Carcinoma with Ganoderma lucidum Extracts (2019)
2. Anti-Cancer Effect of Quercetin in Xenograft Models with EBV-Associated Human Gastric Carcinoma (2016)
3. Quercetin induces protective autophagy in gastric cancer cells: Involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling (2011)
Clinical Trial
1. Dietary quercetin intake and risk of gastric cancer: results from a population-based study in Sweden (2011)
