Oral Cancer

Epigallocatechingallate (EGCG)

1. Epigallocatechin-3-gallate suppresses cell proliferation and promotes apoptosis and autophagy in oral cancer SSC-4 cells

2. The Chemopreventive Properties and Therapeutic Modulation of Green Tea Polyphenols in Oral Squamous Cell Carcinoma

Honokiol

1 .Honokiol inhibits in vitro and in vivo growth of oral squamous cell carcinoma through induction of apoptosis, cell  cycle arrest and autophagy

2. Antitumor activity of 4-O-Methylhonokiol in human oral cancer cells is mediated via ROS generation, disruption of mitochondrial potential, cell cycle arrest and modulation of Bcl-2/Bax proteins

3. Honokiol inhibits sphere formation and xenograft growth of oral cancer side population cells accompanied with JAK/STAT signaling pathway suppression and apoptosis induction

4. Anti-proliferative effect of honokiol in oral squamous cancer through the regulation of specificity protein 1

5. Honokiol Eliminates Human Oral Cancer Stem-Like Cells Accompanied with Suppression of Wnt/-Catenin Signaling and Apoptosis Induction

Luteolin

1. Chemotherapeutic effects of luteolin on radio-sensitivity enhancement and interleukin-6/ signal transducer and activator of transcription 3 signaling repression of oral cancer stem cells

Lycopene

In Vitro

1. Lycopene Inhibits Proliferation and Enhances Gap-Junction Communication of KB-1 Human Oral Tumor Cells

In Vivo

1. Histological and immunohistochemical evaluation of the chemopreventive role of lycopene in tongue carcinogenesis induced by 4-nitroquinoline-1-oxide

Clinical Trials

1. To determine the efficacy of lycopene as compared to multivitamin preparation in the treatment of Oral Submucous Fibrosis

2. Role of lycopene in oral potentially malignant disorders

3. Role of lycopene in the prevention of oral precancerous lesions. A Review

4. Anti‐inflammatory Dietary Supplements in the Chemoprevention of Oral Cancer.

5. LYCOPENE: POTENT ANTIOXIDANT FOR ORAL PREMALIGNANCY AND ORAL CANCER

6. Role of Lycopene in Preventing Oral Diseases as a Nonsurgical Aid of Treatment

7. Comparative study of the efficacy of lycopene and aloe vera in the treatment of oral submucous fibrosis

8. Randomized controlled trial to evaluate the efficacy of oral lycopene in combination with vitamin E and selenium in the treatment of oral leukoplakia

9. LYCOPENE – ROLE IN CANCER PREVENTION

10. Lycopene in oral health

11. LYCOPENE IN THE MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS

12. The Response of Oral Submucous Fibrosis to Lycopene – A Carotenoid Antioxidant: A Clinicopathological Study

13. Efficacy of oral lycopene in the treatment of oral leukoplakia

14. Response of lycopene in treatment of oral submucous fibrosis

Quercetin

1. Efficacy of quercetin against chemically induced murine oral squamous cell carcinoma

2. Quercetin Inhibits Migration and Invasion of SAS Human Oral Cancer Cells through Inhibition of NF-κB and Matrix Metalloproteinase-2/-9 Signaling Pathways

Spirulina platensis

1. Cytotoxicity of Spirulina Extract on Oral Cancer Cell Lines

Tinospora cordifolia

1. Tinospora Cordifolia Induces Cell Cycle Arrest in Human Oral Squamous Cell Carcinoma Cells

Vitamin C

1. Status of Serum and Salivary Ascorbic Acid in Oral Potentially Malignant Disorders and Oral Cancer