Int. Research of Resveratrol

General Anti-cancer Activities

Bladder Cancer

1.Effect and mechanism of resveratrol on drug resistance in human bladder cancer cells

2.Short-Term Resveratrol Exposure Causes In Vitro and In Vivo Growth Inhibition and Apoptosis of Bladder Cancer Cells

3.Resveratrol induces apoptosis associated with mitochondrial dysfunction in bladder carcinoma cells

Bone Cancer

1.Induction of sirtuin-1 signaling by resveratrol induces human chondrosarcoma cell apoptosis and exhibits antitumor activity

2.Antitumor effect of resveratrol on chondrosarcoma cells via phosphoinositide 3 kinase/AKT and p38 mitogen-activated protein kinase pathways

3.Resveratrol inhibits canonical Wnt signaling in human MG-63 osteosarcoma Cells

4.Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas

Brain Cancer

1.Resveratrol Impairs Glioma Stem Cells Proliferation and Motility by Modulating the Wnt Signaling Pathway

2.Resveratrol inhibits glioma cell growth via targeting oncogenic microRNAs and multiple signaling pathways

3.Resveratrol and quercetin cooperate to induce senescence-like growth arrest in C6 rat glioma cells

4.Inhibition of STAT3 Expression and Signaling in Resveratrol-Differentiated Medulloblastoma Cells

Breast Cancer In Vitro

1.Resveratrol chemosensitizes HER-2-overexpressing breast cancer cells to docetaxel chemoresistance by inhibiting docetaxel-mediated activation of HER-2–Akt axis

2.Resveratrol-induced cyclooxygenase-2 facilitates p53-dependent apoptosis in human breast cancer cells

In Vivo

1.Resveratrol Attenuates the Anticancer Efficacy of Paclitaxel in Human Breast Cancer Cells In Vitro and In Vivo

Colorectal Cancer

1.Resveratrol Inhibits Invasion and Metastasis of Colorectal Cancer Cells via MALAT1 Mediated Wnt/-Catenin Signal Pathway

2.Modulatory role of resveratrol on cytotoic activity of cisplatin, sensitization and modification of cisplatin resistance in colorectal cancer cells

3.Resveratrol Suppresses Colitis and Colon Cancer Associated with Colitis

4.Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways

5.Curcumin Synergizes With Resveratrol to Inhibit Colon Cancer

Gastric Cancer

1.Resveratrol induces cell cycle arrest in human gastric cancer MGC803 cells via the PTEN‑regulated PI3K/Akt signaling pathway

2.Resveratrol: A potential challenger against gastric cancer

3.Resveratrol Inhibits the Growth of Gastric Cancer by Inducing G1 Phase Arrest and Senescence in a Sirt1- Dependent Manner

Liver Cancer

1.By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice

2.Chemoprevention of HBV-related hepatocellular carcinoma by the combined product of resveratrol and silymarinin transgenic mice

3.Synergistic anticancer effects of curcumin and resveratrol in Hepa1-6 hepatocellular carcinoma cells

4.The Antimetastatic Effects of Resveratrol on Hepatocellular Carcinoma through the Downregulation of a Metastasis-Associated Protease by SP-1Modulation

Lung Cancer In Vitro

1.Resveratrol raises in vitro anticancer effects of paclitaxel in NSCLC cell line A549 through CO X-2 expression

2.Resveratrol overcomes gefitinib resistance by increasing the intracellular gefitinib concentration and triggering apoptosis, autophagy and senescence in PC9/G NSCLC cells

3.Resveratrol enhanced anticancer effects of cisplatin on non-small cell lung cancer cell lines by inducing mitochondrial dysfunction and cell apoptosis

4.Resveratrol Enhances Etoposide-Induced Cytotoxicity through Down-Regulating ERK1/2 and AKT-Mediated X-ray Repair Cross-Complement Group 1 (XRCC1) Protein Expression in Human Non-Small-Cell Lung Cancer Cells

5.Anti-Inflammatory and Pro-apoptotic Effects of Curcumin and Resveratrol on the Human Lung Fibroblast Cell Line MRC-5

6.Resveratrol Modulates Expression of ABC Transporters in Non-Small Lung Cancer Cells: Molecular Docking and Gene Expression Studies

7.Resveratrol Induces Premature Senescence in Lung Cancer Cells via ROS-Mediated DNA Damage

8.Resveratrol Alters microRNA Expression Profiles in A549 Human Non-Small Cell Lung Cancer Cells

9.Molecular Mechanisms of Resveratrol Action in Lung Cancer Cells Using Dual Protein and Microarray Analyses

10.Resveratrol enhances ionizing radiation-induced premature senescence in lung cancer cells

11.Resveratrol Enhances Radiosensitivity of Human Non-Small Cell Lung Cancer NCI-H838 Cells Accompanied by Inhibition of Nuclear Factor-Kappa B Activation

12.Resveratrol Induces Growth Inhibition, S-phase Arrest, Apoptosis, and Changes in Biomarker Expression in Several Human Cancer Cell Lines

In Vivo

1.Effects of Resveratrol against Lung Cancer: In Vitro and In Vivo Studies

2.Resveratrol in lung cancer- a systematic review

3.In vitro and in vivo Evaluation of the Antitumor Efficiency of Resveratrol Against Lung Cancer

4.Study to Evaluate Molecular Mechanics behind Synergistic Chemo-Preventive Effects of Curcumin and Resveratrol during Lung Carcinogenesis

5.Analysis of resveratrol as a lung cancer chemopreventive agent in A/J mice exposed to benzo[]pyrene

Oesophageal Cancer

1.A dietary pattern rich in lignans, quercetin and resveratrol decreases the risk of oesophageal cancer

2.Suppression of N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumorigenesis in F344 rats by resveratrol

3.Resveratrol induces apoptosis in human esophageal carcinoma cells

Oral Cancer

1.MOLECULAR DOCKING STUDIES OF RESVERATROL AGAINST THE HUMAN ORAL CANCER CELL LINE PROTEINS (KB CELLS)

Ovarian Cancer In Vitro

1.Apoptotic Cell Death Induced by Resveratrol Is Partially Mediated by the Autophagy Pathway in Human Ovarian Cancer Cells

2.Resveratrol Inhibits Cisplatin-Induced Epithelial-to-Mesenchymal Transition in Ovarian Cancer Cell Lines

In Vivo

1.Resveratrol Exerts Differential Effects in Vitro and in Vivo against Ovarian Cancer Cells

2.Resveratrol Suppresses Growth of Human Ovarian Cancer Cells in Culture and in a Murine Xenograft Model: Eukaryotic Elongation Factor 1A2 as a Potential Target

Pancreatic Cancer

1.Effect of resveratrol on proliferation and apoptosis of human pancreatic cancer MIA PaCa-2 cells may involve inhibition of the Hedgehog signaling pathway

2.Resveratrol, a Red Wine Polyphenol, Suppresses Pancreatic Cancer by Inhibiting Leukotriene A4 Hydrolase

3.Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer

Prostate Cancer

1.Resveratrol Reduces Prostate Cancer Growth and Metastasis by Inhibiting the Akt/MicroRNA-21 Pathway

2.Resveratrol-caused apoptosis of human prostate carcinoma LNCaP cells is mediated via modulation of phosphatidylinositol 3´-kinase/Akt pathway and Bcl-2 family proteins

3.Resveratrol: A Candidate Nutritional Substance for Prostate Cancer Prevention

Renal Cell Carcinoma

1.Resveratrol promotes regression of renal carcinoma cells via a renin angiotensin system suppression dependent mechanism

2.Resveratrol attenuates constitutive STAT3 and STAT5 activation through induction of PTPε and SHP-2 tyrosine phosphatases and potentiates sorafenib-induced apoptosis in renal cell carcinoma

3.Effects of Resveratrol on Gene Expression in Renal Cell Carcinoma

Skin Cancer

1.Administration of resveratrol enhances cell-cycle arrest followed by apoptosis in DMBA-induced skin carcinogenesis in male Wistar rats

2.The inhibition of resveratrol to human skin squamous cell carcinoma A431 xenografts in nude mice

3.Resveratrol Modulates the Malignant Properties of Cutaneous Melanoma via Changes in the Activation and Attenuation of the Anti-apoptotic Proto-oncogenic Protein Akt/PKB

Thyroid Cancer

1.Resveratrol Sensitizes Selectively Thyroid Cancer Cell to 131-Iodine Toxicity

2.Resveratrol Induces Differentiation Markers Expression in Anaplastic Thyroid Carcinoma via Activation of Notch1 Signaling and Suppresses Cell Growth

3.Resveratrol Induces Apoptosis in Thyroid Cancer Cell Lines via a MAPK- and p53-Dependent Mechanism